Job Description

Scientist - Analytical Chemistry

Job Summary:
The Gene Therapy group is seeking to hire a Scientist to become an integral part of the gene therapy drug development effort. We seek candidates who think critically and have the desire and ability to learn new techniques. This position requires adaptability and an ability to perform at a high level in a fast-paced environment. The ideal candidate will leverage their mass spectrometry and chromatography expertise to develop assays in support of their gene therapy programs.  
Qualifications:

• Ph.D. with 2+ years or M.S. with 6+ years of industry experience in analytical chemistry, chemical biology, biochemistry or a related field. 

• Creativity and the ability to work within an interdisciplinary team to achieve technical and corporate milestones. 

• Ability to thrive in a fast-paced, start-up environment. 

• Strong verbal and written communication, critical thinking, and problem-solving skills. 

Technical Requirements and Skills:

• Extensive expertise in the development of analytical assays to support drug product characterization, including LC/UV, LC/MS, CE, and biochemical readouts. 

• Successful development of proteomic and metabolic assays is preferred. 

• Knowledge of purification with different chromatography methods including HPLC, IEX, and SEC for protein conjugations. 

• Previous experience using state-of-the-art LC-MS equipment for MRM/SRM and TOF analysis (Shimadzu,?Agilent, Waters, ExionLC AE, Sciex). 

• Analyze proteomics data using proteomics analysis software (Skyline) and bioinformatics tools for protein and peptide quantification. 

• Working knowledge with recombinant protein downstream purification and characterization. 

• Research literature and external sources and identify new techniques and procedures. 

• Ideal candidate will have familiarity with ELNs (i.e. Benchling), Olink-based proteomics, MSD, Western blot, metabolomics and unbiased proteomics analysis. 

• Strong record-keeping and organizational skills. 

Compensation: 125K-150k
Benefits
? Equity and ownership in a fast-growing company.

? Access to a 24-hour gym

? Comprehensive medical, dental, and vision

? Commuting stipend based on your geographical location

? 401(k) Match: offers a dollar-for-dollar match

? All full-time employees are eligible for our flexible time off policy

Job Tags

Permanent employment, Full time, Flexible hours,

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